It provides to get doze than standards to increase the chance of treatment and extend a period of deterioration such as at the types of Organ Transplantation, Lymphoma, and Leukemia. It means there is deterioration in the place where there is no indicator of Ca. Chemotherapy, which is sometimes applied overdoses with radiotherapy is almost given more than one or two days. The overdose treatment damages to bone medulla and root cells.
Consequently following the overdose treatment you are implanted from your root cell (otology treatment) or the Donor's (allogeneic)
The Overdose Chemotherapy Backed Root Cell
In some types of Ca, the overdose chemotherapy Is given. It is generally applied for the Ca which entertains a high risk of relapse Lymphoma or the processing of bone medulla transplantation. The Overdose of chemotherapy damages the bone medulla (makes blood cells) in general, but the root cell can provide blood production again. These root cells (before the overdose treatment] can collected from the patient or from a person whose cells are completely compromised. This kind of application is for the type of Ca below.
- Relapse Lymphoma
- Acute Leukemia
- Aplastic Anemia
- Multiple Myeloma
- Myelodysplastic Syndromes
- Thalassemia
- Relapse Tumors of Reproduction Cells
The overdose treatment backed root cell is preferred to otology treatments.
The Procedure of Transplantation
Before having treatment, the doctor will explain you the purpose of the treatment. It will be told you that you would have to sign an approval form for application of this treatment, will done by the hospital staff. First step is; to take the Leukemia or Ca down the lowest level as possible as by using cemotheraphy or/and radiotheraphy. The best one is in the overdose period, not being any identifiable Ca (means that there is deterioration). It gives the maximal chance to prove treatment useful. Nometheless, if there is still Ca on a small scale, the treatment will considered that it proved useful. Second step is collecting the stem cells from you or donor. It is known like harvest. The third step is overdose treatment. The purpose is to clean any type of Ca which is standed on your body. Only the cemotheraphy is able to apply you. Sometimes at the same time the radiotheraphy is applied. This intensive treatment wills also completely damage your full normal bones. This step is called as cure dose and only goes on one or two days. This cause you perceive bad and also it is done nausea. The Medications (anti-emetic] will given you to prevented nausea, is also opiate.
These kind of medications are very effective and generally can get control the feeling of nausea and vomiting. The forth step is giving the stem cells by a DRIP. It is bit blood transplantation. To finding the way into the bone marrow by blood stream of the cells and to start to cell production for you, 2-4 weeks will be passed. You have to hospitalize until your blood cells number come to a confidential level into your blood stream. If your healty blood cell level is low, you have to use antibiotic. It is because of your low resistance prevent you from the infections, you can also taken care on your own room. You will permanently need support of medications and nursing through this duration.
Oncology Health Packages
The Division of Hematology/Oncology offers hematological and oncological services, with special expertise in hematological malignancies, bone marrow transplantation solid tumors, red blood cell disorders and immunological diseases. In multidisciplinary conferences for specific forms of cancer, members of the Division join physicians from surgery, radiology, pathology, and other disciplines to review patient problems and potential treatment modalities.
Laboratory services include a highly sophisticated blood bank, servicing complex marrow and organ transplant programs.
Staff physicians participate in multidiscliplinary clinics that provide comprehensive diagnostic and treatment evaluations for benign and malignant disorders in:
- Stem Cell Transplant Unit
- Biotherapy Unit
- The Breast Health Center
- The G.I and Colorectal Cancer Center
- The Lung and Tumor Evaluation Center
- The head and Neck Tumor Center
- The Stem Cell Collection and Cryopreservation Unit
- The Cellular Theraphy Laboratory
- The Oncology and Hematology Infusion Center The Extracorporeal Photopheresis Unit
- The Cutaneous T-Cell Lymphoma Program
- The Hematological Malignancy Program
- The Bone Marrow and Hematopoietic Stem Cell Transplantation Program
- The Lymphoma and Experimental Therapeutics Program
- The Breast Cancer Program
- The 4-bed Infusion Center is a state-of-the-art facility that provides chemotheraphy, parenteral antibiotics, and infusional support, in addition to education and psychosocial services. The Center for Extracorporeal Photopheresis provides novel therapy for graft versus host disease (GvHD).
Hematopoietic stem cell and marrow transplantation are important programs within the Division.
The transplant unit is certified by Ministry of Health and EBMT for conduct of autologous, allogeneic, matched-unrelated and reduced intensity transplants.
Transplant unit is also certified as Unrelated Donor Harvests by EBMT. The Unit is supported by the Extracorporeal Photopheresis unit that is supervised and maintained by the Division.
Hematology/Oncology Division Introduction
The Division of Hematology/Oncology is responsible for inpatient, outpatient and consultative services in the fields Hematology and Oncology, transfusion medicine, and hematopoietic cell transplantation. The special hematology laboratories are under the direct supervision of the Division. In addition,the clinical programs of the Blood Bank are also coordinated included in the training program of the Division. The Division's research continues to develop and refine new therapies for malignant disorders and to train future leaders within a comprehensive Oncology Fellowship Program for successful careers in academic Oncology and Stem Cell Transplantation.
The Hematological Malignancy and Bone Marrow and Hematopoietic Stem Cell Transplantation Programs include clinical research in high dose chemotheraphy and long-term outcome for bone marrow transplants. The Bone Marrow Transplantation Program is a comprehensive service that performs both autologous and allogeneic transplants, peripheral progenitor, matched unrelated and reduced intensity transplants. It has pioneered utilization of extracorporeal photopheresis in acute graft versus host disease following allogeneic stem cell transplantation. The Bone Marrow Transplantation Multidisciplinary Team is comprised of physicians, nurses, pharmacists, therapists, social workers and administrators specializing in all aspects of stem cell transplantation for adult patients. The Bone Marrow Transplantation Program is heavily supported by specialty programs based in the Divisions of Intensive Care Unit, Pulmonary Medicine, Infectious Diseases, Renal Medicine and other specialty services of the Medical Center.
