Nephrology
  • Interests
  • Hypertension
  • Acute Kidney Injury
  • Chronic Kidney Disease
  • Dialysis
  • Kidney Transplantation
  • Proteinuria
  • Electrolyte Imbalance
Nephrology
  • Interests
  • Hypertension
  • Acute Kidney Injury
  • Chronic Kidney Disease
  • Dialysis
  • Kidney Transplantation
  • Proteinuria
  • Electrolyte Imbalance
İSÜ Medical Park Gaziosmanpaşa (Gaziosmanpaşa)
Merkez Mahallesi, Çukurçeşme Cd. 57-59, 34250 Gaziosmanpaşa/İstanbul - İstanbul

İSÜ Medical Park Gaziosmanpaşa (Gaziosmanpaşa)
Merkez Mahallesi, Çukurçeşme Cd. 57-59, 34250 Gaziosmanpaşa/İstanbul - İstanbul

Academic Background

Education and Specialization
1995 Istanbul University, Istanbul Faculty of Medicine
2001 Uludağ University, Faculty of Medicine, Department of Internal Medicine - Internal Medicine Residency
2009 Istanbul University, Istanbul Faculty of Medicine, Department of Internal Medicine, Division of Nephrology - Nephrology Residency

Experience
2009-2011 - Malatya State Hospital
2011 - Associate Professor
2011-2014 - Private Memorial Şişli and Hizmet Hospital Transplantation Clinic
2014-2015 - Private Medipol Mega Hospital Nephrology and Transplantation Clinic
2016-2018 - Associate Professor and Faculty Member, Health Sciences University Faculty of Medicine
2018-2023 - Professor and Faculty Member, Health Sciences University Faculty of Medicine
2016-2023 - Training Supervisor, Internal Medicine Clinic, Istanbul Bağcılar Training and Research Hospital, Health Sciences University

Professional Memberships

  1. Turkish Society of Nephrology
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Scientific Publications

Publications in International Peer-Reviewed Journals

  1. Berna Yelken, Sule Namli, Numan Gorgulu, and Tevfik Ecder. Focal segmental glomerulosclerosis associated with Good’s syndrome. NDT Plus 2008;(1):26-27.

  2. Yasar Caliskan, Halil Yazici, Numan Gorgulu, Berna Yelken, Turker Emre, Aydin Turkmen, Alaattin Yildiz, Nilgun Aysuna, Semra Bozfakioglu, Mehmet Sukru Sever. Effect of pre-transplant dialysis modality on kidney transplantation outcome. Perit Dial Int 2009; 29 Suppl 2.

  3. B. Yelken, N. Gorgulu, Y. Caliskan, A. Elitok, A.O. Cimen, H. Yazici, H. Oflaz, A. Turkmen, M.S. Sever. Association between chronic hepatitis C infection and coronary flow reserve in dialysis patients with failed renal allografts. Transplant Proc 2009;41(5):1519-23.

  4. Yelken BM, Gorgulu N, Caliskan Y, Yazici H, Turkmen A, Yildiz A, Sever MS. Comparison of nutritional status in hemodialysis patients with and without failed renal allografts. Clin Transplant. 2010 Jul;24(4):481-7.

  5. N. Gorgulu, B. Yelken, Y. Caliskan, A. Elitok, O. Cimen, H. Yazici, H. Oflaz, A. Turkmen, S. Bozfakioglu, M.S. Sever. Endothelial dysfunction in peritoneal dialysis patients with and without failed renal transplants. Transplant Proc 2009; 41(9):3647-50.

  6. Yasar Caliskan, Numan Gorgulu, Berna Yelken, Halil Yazici, Huseyin Oflaz, Ali Elitok, Aydin Turkmen, Semra Bozfakioglu, Mehmet Sukru Sever. Plasma ghrelin levels are associated with coronary microvascular and endothelial dysfunction in peritoneal dialysis patients. Ren Fail 2009; 31(9):807-13.

  7. Gorgulu N, Yelken B, Caliskan Y, Elitok A, Cimen AO, Yazici H, Oflaz H, Golcuk E, Ekmekci A, Turkmen A, Yildiz A, Sever MS. Endothelial dysfunction in hemodialysis patients with failed renal transplants. Clin Transplant. 2010 Sep-Oct;24(5):678-84.

  8. Numan Gorgulu, Berna Yelken, Yasar Caliskan, Aydin Turkmen, Mehmet Sukru Sever. Does pregnancy increase graft loss in female renal allograft recipients? Clin Exp Nephrol. 2010 Jun;14(3):244-7.

  9. Numan Gorgulu, Yasar Caliskan, Berna Yelken, Aydin Turkmen. Outcomes of renal transplants from spousal donors: 25 years of experience at our center. Int J Artif Organs. 2010; 33(1):40-44.

  10. Caliskan Y, Gorgulu N, Yelken B, Akturk F, Yazici H, Turkmen A, Sever MS. Serum uric acid level is associated with cardiac hypertrophy in renal transplant recipients. Clin Transplant. 2011;25(3):368-74.

  11. Berna Yelken, Yasar Caliskan, Oktay Ozkan, Numan Gorgulu, Halil Yazici, Aydin Turkmen, and Mehmet S. Sever. Conversion to sirolimus in renal transplant recipients: a single-center experience. Artif Organs. 2010;34(8):230-7.

  12. K. Turkmen, N. Gorgulu, M. Uysal, A. Ozkok, T. Sakaci, A. Unsal, A. Yildiz. Fetuin-A, inflammation, and coronary artery calcifications in hemodialysis patients. Indian J Nephrol 2011;21(2):90-4.

  13. Yasar Caliskan, Berna Yelken, Numan Gorgulu, Abdullah Ozkok, Halil Yazici, Aysegul Telci, Aydin Turkmen, Alaattin Yildiz, and Mehmet S. Sever. Comparison of markers of appetite and inflammation between hemodialysis patients with and without failed renal transplants. J of Ren Nutr. 2012; 22(2):258-267.

  14. Numan Gorgulu, Yasar Caliskan, Berna Yelken, Faruk Akturk, Aydin Turkmen. Effects of arteriovenous fistula on clinical, laboratory and echocardiographic findings in renal allograft recipients. Int J Artif Organs 2011; 34(10): 1024-30.

  15. Berna Yelken, Yasar Caliskan, Numan Gorgulu, Ibrahim Altun, Akar Yilmaz, Halil Yazici, Huseyin Oflaz, and Alaattin Yildiz. Reduction of uric acid levels with allopurinol treatment improves endothelial function in patients with chronic kidney disease. Clin Nephrol 2012; 77(4):275-282.

  16. Yasar Caliskan, Berna Yelken, Abdullah Ozkok, Numan Gorgulu, Halil Yazici, Aysegul Telci, and Alaattin Yildiz. Lower serum prohepcidin levels associated with lower iron and erythropoietin requirements in hemodialysis patients with chronic hepatitis C. BMC Nephrology 2012; 13:56 doi:10.1186/1471-2369-13-56.

  17. Kocak B, Arpali E, Demiralp E, Yelken B, Karatas C, Gorcin S, Gorgulu N, Uzunalan M, Turkmen A, Kalayoglu M. Eculizumab for salvage treatment of refractory antibody-mediated rejection in kidney transplant patients: case reports. Transplant Proc. 2013; 45(3):1022-5.

  18. Yelken B, Gorgulu N, Gursu M, Yazici H, Caliskan Y, Telci A, Ozturk S, Kazancioglu R, Ecder T, Bozfakioglu S. Effects of spironolactone on residual renal function and peritoneal function in peritoneal dialysis patients. Adv Perit Dial. 2014;30:5-10.

  19. Bennur Esen, Ahmet Engin Atay, Irfan Sahin, Emel Saglam Gokmen, Suat Hayri Kucuk, Sefik, Eser Ozyurek, Ozlem Kaptanogullari, and Numan Gorgulu. The relation of serum 25-hydroxy vitamin D3 with inflammation and indirect markers of thrombotic activity in patients with end-stage renal disease. J Clin Exper Nephrol 2016; Vol.1 No:2:9.

  20. Bennur Esen, Tarik Sayin, Halit Akbas, Emel Saglam Gokmen, Ahmet Engin Atay, Saadet Pilten Guzel, Numan Gorgulu, and Dilek Gogas Yavuz. The role of E-selectin level and E-selectin gene S128R polymorphism on the enlargement of renal cyst in patients with polycystic kidney disease: Genetic background of renal cyst growth. Clinical Nephrology 2019; Vol.

  21. Enes Aral, Zeyneb Baspehlivan Tuzcu, Murselin Guney, Arif Savas, Cem Cemal Balaban, Emel Saglam Gokmen, Numan Gorgulu, Ahmet Engin Atay. The relation of bone mineral density with the serum levels of 25-hydroxy vitamin D in premenopausal and postmenopausal individuals: Vitamin D and bone health. IJBCS 2020; 9(2): 96-104.

  22. Turgutalp K, Ozturk S, Arici M, Eren N, Gorgulu N, Islam M, Uzun S, Sakaci T, Aydin Z, Sengul E, Demirelli B, Ayar Y, Altiparmak MR, Sipahi S, Mentes IB, Ozler TE, Oguz EG, Huddam B, Hur E, Kazancioglu R, Gungor O, Tokgoz B, Tonbul HZ, Yildiz A, Sezer S, Odabas AR, Ates K. Determinants of mortality in a large group of hemodialysis patients hospitalized for COVID-19. BMC Nephrol. 2021 Jan 14;22 (1):29.

  23. Oto OA, Ozturk S, Turgutalp K, Arici M, Alpay N, Merhametsiz O, Sipahi S, Ogutmen MB, Yelken B, Altiparmak MR, Gorgulu N, Tatar E, Ozkan O, Ayar Y, Aydin Z, Dheir H, Ozkok A, Safak S, Demir ME, Odabas AR, Tokgoz B, Tonbul HZ, Sezer S, Ates K, Yildiz A. Predicting the outcome of COVID-19 infection in kidney transplant recipients. BMC Nephrol. 2021 Mar 19;22(1):100.

  24. Öztürk S, Turgutalp K, Arici M, Çetinkaya H, Altiparmak MR, Aydin Z, Soypacak Z, Bora F, Kara E, Cebeci E, Özler TE, Dölarslan ME, Sipahi S, Ayar Y, Şahin İ, Bakirdogen S, Islam M, Görgülü N, Ogutmen MB, Şengul E, Güngör Ö, Seyahi N, Tokgoz B, Odabas AR, Tonbul HZ, Sezer S, Yildiz A, Ates K. Impact of hospital-acquired acute kidney injury on COVID-19 outcomes in patients with and without chronic kidney disease: A multicenter, retrospective cohort study. Turk J Med Sci. 2021 Jun 28;51(3):947-961.

  25. Ozturk S, Turgutalp K, Arici M, Gorgulu N, Tonbul HZ, Eren N, Gencer V, Ayli MD, Pembegul I, Dolarslan ME, Ural Z, Colak H, Ozler TE, Can O, Demir ME, Altunoren O, Huddam B, Onec K, Demirelli B, Aydin Z, Altun E, Alagoz S, Ayar Y, Eser ZE, Berktas B, Yilmaz Z, Ates EU, Yuksel E, Sahin GK, Aktar M, Cebeci E, Dursun B, Kocak SY, Yildiz A, Kazan S, Gok M, Sengul E, Tugcu M, Ozturk R, Kahvecioglu S, Kara E, Kaya B, Sahin G, Sakaci T, Sipahi S, Kurultak I, Durak BA, Altiparmak MR, Ecder SA, Karadag S, Dincer MT, Ozer H, Bek SG, Ulu MS, Gungor O, Bakir EA, Odabas AR, Seyahi N, Yildiz A, Ates K. The longitudinal evolution of post-COVID-19 outcomes among hemodialysis patients in Turkey. Kidney Int Rep. 2022 Jun;7 (6):1393-1405.

  26. Alagoz S, Eren N, Ozcan SG, Atlı Z, Ozkul O, Belli H, Gorgulu N, Seyyar M, Seyahi N. Impact of COVID-19 lockdown on mood status: A comparison of hemodialysis and oncology patients. Ther Apher Dial. 2022 Aug;26 (4):781-789.

  27. Oto OA, Ozturk S, Arici M, Velioglu A, Dursun B, Guller N, Şahin İ, Eser ZE, Paydas S, Trabulus S, Koyuncu S, Uyar M, Ural Z, Sadioglu RE, Dheir H, Koç NS, Özer H, Durak BA, Gül CB, Kasapoglu U, Oguz EG, Tanrisev M, Kuzgun GS, Mirioglu S, Dervisoglu E, Erken E, Gorgulu N, Ozkurt S, Aydin Z, Kurultak I, Ogutmen MB, Bakirdogen S, Kaya B, Karadag S, Ulu MS, Gungor O, Bakir EA, Odabas AR, Seyahi N, Yildiz A, Ates K. Middle-term outcomes in renal transplant recipients with COVID-19: A national, multicenter, controlled study. Clin Kidney J. 2022 Feb 14;15(5):999-1006.

  28. Karadag S, Ozturk S, Arici M, Gorgulu N, Akcali E, Pembegul I, Taymez DG, Kazancioglu R, Ayar Y, Mutluay R, Ozdemir A, Aydin Z, Bashan Y, Alagoz S, Yilmaz F, Trabulus S, Dirim AB, Ozturk I, Inci A, Azak A, Aktas N, Kuzu T, Dheir H, Basturk T, Ozler TE, Dincer MT, Turgutalp K, Ulu S, Gungor O, Bakir EA, Odabas AR, Seyahi N, Yildiz A, Ates. Post-COVID-19 outcomes of non-dialysis-dependent chronic kidney disease patients: A national, multicenter, controlled study. Urol Nephrol. 2023 Feb;55(2): 399-408.

  29. Saglam E, Sener G, Bayrak T, Bayrak A, Gorgulu N. Analysis of ischemia-modified albumin (IMA) and coagulation parameters in patients with SARS-CoV-2 pneumonia. J Clin Med. 2023 Jun 27;12(13): 4304.Publications in National Peer-Reviewed Journals

    1. Serdar Kahvecioğlu, İbrahim Akdağ, Numan Görgülü, Serkan Torun, Mahmut Arabul, Ömer Fatih Ölmez, Mustafa Güllülü, Alpaslan Ersoy, Kamil Dilek, Mahmut Yavuz. Frequency and findings of amyloidosis in Familial Mediterranean Fever. Okmeydanı Training and Research Hospital Medical Journal 2005; 22(1):51-3.

    2. Serdar Kahvecioğlu, Numan Görgülü, İbrahim Akdağ, Celaleddin Demircan, Tuncay Dağel, Alpaslan Ersoy, Kamil Dilek, Mustafa Güllülü, Mahmut Yavuz. Cases of multiple myeloma presenting with acute renal failure. Okmeydanı Training and Research Hospital Medical Journal 2005; 22(3):53-5.

    3. Serdar Kahvecioğlu, İbrahim Akdağ, Mahmut Arabul, Numan Görgülü, Alpaslan Ersoy, Mustafa Güllülü, Mahmut Yavuz, Kamil Dilek, Mustafa Yurtkuran. Dialysis and erectile dysfunction. Uludağ University Faculty of Medicine Journal 2005; 31(1):1-4.

    4. Serdar Kahvecioğlu, İbrahim Akdağ, Numan Görgülü, Mahmut Yavuz, Mahmut Arabul, Tuncay Dağel, Mustafa Güllülü, Alpaslan Ersoy, Kamil Dilek. Tertiary hyperparathyroidism and hungry bone syndrome. Okmeydanı Training and Research Hospital Medical Journal 2006; 23(1):54-6.

    5. Serdar Kahvecioğlu, Numan Görgülü, İbrahim Akdağ, Celaleddin Demircan, Canan Evci, Tuncay Dağel, Emel Yılmaz, Alpaslan Ersoy, Kamil Dilek, Mustafa Güllülü. Pulmonary geotrichosis infection in a patient with sepsis following renal biopsy. Okmeydanı Training and Research Hospital Medical Journal 2006; 23(1):44-6.


    Papers Presented at International Scientific Meetings and Published in Proceedings

    1. Numan Gorgulu, Berna Yelken, Yasar Caliskan, Ali Elitok, Halil Yazici, Turker Emre, Huseyin Oflaz, Alaattin Yildiz, Aydin Turkmen, Nilgun Aysuna, Mehmet Sukru Sever. Endothelial dysfunction is more prominent in hemodialysis patients with failed transplant and chronic hepatitis C infection. ERA-EDTA Congress NDT Plus SP331 ii 138 May 10-13, 2008 Stockholm, Sweden.

    2. Caliskan Y., Yazici H., Görgülü N., Yelken B., Emre T., Turkmen A., Yildiz A., Aysuna N., Bozfakioglu S., Sever M.S. Effect of pre-transplant dialysis modality on kidney transplantation outcome. ISPD Congress Peritoneal Dialysis International OP-18, S7, June 20-24, 2008 Istanbul, Turkey.

    3. Görgülü N., Yelken B., Caliskan Y., Elitok A., Yazici H., Emre T., Oflaz H., Turkmen A., Sever M., Bozfakioglu S. Endothelial dysfunction is associated with inflammation in patients with failed renal transplants on PD. ISPD Congress Peritoneal Dialysis International PP-162 S56, June 20-24, 2008 Istanbul, Turkey.

    4. Caliskan Y., Görgülü N., Yelken B., Yazici H., Elitok A., Emre T., Kocak H., Turkmen A., Yildiz A., Aysuna N., Sever M.S., Bozfakioglu S. Relationship between serum ghrelin levels and endothelial dysfunction in peritoneal dialysis patients. ISPD Congress Peritoneal Dialysis International PP-163, S57, June 20-24, 2008 Istanbul, Turkey.

    5. Yelken B., Görgülü N., Caliskan Y., Elitok A., Yazici H., Emre T., Oflaz H., Turkmen A., Sever M.S., Bozfakioglu S. Effects of secondary hyperparathyroidism and inflammation on endothelial function in PD patients. ISPD Congress Peritoneal Dialysis International PP-183, S62, June 20-24, 2008 Istanbul, Turkey.

    6. Caliskan Y., Yelken B., Görgülü N., Yazici H., Iyidogan Y., Emre T., Turkmen A., Yildiz A., Aysuna N., Bozfakioglu S., Sever M.S. Association of serum ghrelin and leptin levels with nutrition and inflammatory status in chronic renal disease. ISPD Congress Peritoneal Dialysis International PP-304, S92, June 20-24, 2008 Istanbul, Turkey.

    7. Yasar Caliskan, Numan Görgülü, Berna Yelken, Abdullah Özkök, Halil Yazici, Aysegul Telci, Alaattin Yildiz, Mehmet Sukru Sever. Comparison of nutrition and inflammation markers in hemodialysis patients with and without failed renal allografts. BANTAO Congress Abstract Book OP-05, P7, November 2009 Antalya, Turkey.


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