Pediatric Immunology and Allergic Diseases
  • Interests
  • Astım
  • Allerjik Rinit
  • Atopik Dermatit
  • Besin Alerjisi
  • İlaç Alerjisi
  • İmmünoterapi
  • Tekrarlayan Enfeksiyon
  • İmün Yetmezlik
Pediatric Immunology and Allergic Diseases
  • Interests
  • Astım
  • Allerjik Rinit
  • Atopik Dermatit
  • Besin Alerjisi
  • İlaç Alerjisi
  • İmmünoterapi
  • Tekrarlayan Enfeksiyon
  • İmün Yetmezlik
Medical Park Göztepe Hastane Kompleksi (Kadıköy)
Merdivenköy Mahallesi, E5 Üzeri, 23 Nisan Sok. No:17, 34732 Merdivenköy/Kadıköy/İstanbul - İstanbul

Medical Park Göztepe Hastane Kompleksi (Kadıköy)
Merdivenköy Mahallesi, E5 Üzeri, 23 Nisan Sok. No:17, 34732 Merdivenköy/Kadıköy/İstanbul - İstanbul

Academic Background

Eğitim ve Uzmanlık
1999-2005 Üniversite Gülhane Askeri Tıp Akademisi- Ankara
2008-2012 Uzmanlık Zeynep Kamil Eğitim ve Araştırma Hastanesi, Çocuk Sağlığı ve Hastalıkları
2014-2017  Yan-Dal  Uzmanlık Cerrahpaşa Tıp Fakültesi, Çocuk Allerji ve İmmunoloji Bilim Dalı                                   
2017-2017 Observer Laboratory of Human Genetics of Infectious Diseases, Rockefeller University, New York
2018-2018 Uzm. Dr. Özel Eskişehir Acıbadem Hastanesi
2018-2019Uzm. Dr. Başkent Üniveristesi -İstanbul 
2019-2022 Dr. Öğr. Üye İstanbul Medipol Üniveristesi

Kurs ve Sertifikalar
İlaç Alerjisi Kursu - Mayıs 2017
Akan Hücre Ölçer Kursu - Eylül 2018
Primer İmmün Yetersizlik Kursu - Kasım 2019
Besin Allerjisi – Kursu – Mart 2017
İlaç Allerjileri Kursu - Aralık 2015

Mesleki Üyelikler
Türkiye Ulusal Allerji Klinik Immunoloji Derneği
Avrupa Allerji Klinik Immunoloji Derneği
Avrupa İmmün Yetmezlik Derneği
Çocuk Allerji ve Astım Akademisi Derneği
Türk İmmunoloji Derneği

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Scientific Publications

Araştırma ve Yayınlar
Yayınlar
1-Uluslararası hakemli dergilerde yayınlanan makaleler (SCI,SSCI,ArtsandHumanities)

.,1) Inherited IL-17RA deficiency in patients with fungal  and bacterial diseases: Genetic, immunological, and clinical features
Romain Lévya,b,c, Satoshi Okadac,d,1, Vivien Béziata,b,1, Kunihiko Moriyaa,b,1, Caini Liue , Louis Yi Ann Chaia,b,2, Mélanie Migauda,b, Fabian Hauckf , Amein Al Alig , Cyril Cyrusg , Chittibabu Vatteg , Turkan Patirogluh , Ekrem Unalh , Marie Ferneinyi , Nobuyuki Hyakunaj , Serdar Nepesov , Matias Oleastrol , Aydan Ikinciogullarim, Figen Dogum, Takaki Asanod , Osamu Oharan , Ling Yuna,b, Erika Della Minaa,b, Didier Bronnimanna,b, Yuval Itanc , Florian Gothef , Jacinta Bustamantea,b,c,o, Stéphanie Boisson-Dupuisa,b,c, Natalia Tahuilp,3, Caner Aytekinq,3, Aicha Salhir,3, Saleh Al Muhsens,3, Masao Kobayashid,3, Julie Toubianat,3, Laurent Abela,b,c,3, Xiaoxia Lie,3, Yildiz Camciogluu,3, Fatih Celmeliv,3, Christoph Kleinf,3, Suzan A. AlKhaterw,3, Jean-Laurent Casanovaa,b,c,x,y,4,5, and AnnePuela,Contributed by Jean-Laurent Casanova, November 10, 2016 (sent for review August 29, 2016; reviewed by Kai Kisand and Mikko Seppanen) PNAS Early Edition

2) A Case of Brucella Admitting With Bicytopenia And DeepThrombocytopenia
Deniz AYGÜN,Ayşe Ayzıt ATABEK, Serdar NEPESOV,Haluk ÇOKUĞRAŞ, Yıldız Camcıoğlu
Turkis Pediatric Association Young Pediatrician Current and Scientific Medical Journal september-2016

3) Presentation of H-Type Tracheoesophageal Fistula in Two Adolescents: Delayed Diagnosis.
Aygun D, Emre S, Nepesov S, Tekant G, Cokugras H, Camcıoglu Y.
Pediatr Neonatol. 2016 Apr 29. pii: S1875-9572(16)30037-7. doi: 10.1016/j.pedneo.2015.10.016. [Epub ahead of print]

4) Bladder Wall Telangiectasia in a Patient with Ataxia-Telangiectasia and How to Manage?
Aygün FD, Nepesov S, Çokuğraş H, Camcıoğlu Y.
Case Rep Pediatr. 2015;2015:615368. doi: 10.1155/2015/615368

5) Inherited IL-17RC deficiency in patients with chronic mucocutaneous candidiasis.
Ling Y, Cypowyj S, Aytekin C, Galicchio M, Camcioglu Y, Nepesov S, Ikinciogullari A, Dogu F, Belkadi A, Levy R, Migaud M, Boisson B, Bolze A, Itan Y, Goudin N, Cottineau J, Picard C, Abel L, Bustamante J, Casanova JL, Puel A.
J Exp Med. 2015 May 4;212(5):619-31. doi: 10.1084/jem.20141065.

6)  Salmonella Bacteremia: Pay Attention to Chronic Granulomatous Disease
Fatma Deniz Aygün , Fatih Aygün , Serdar Nepesov , Halit Çam , Yıldız Camcıoğlu
Journal of Clinical and Analytical Medicine  2015;6(suppl 5): 695-7 Case report

7) A Medical Nightmare: Anaphylaxis
Serdar Nepesov
,Haluk Çokuğraş
Clinical medical pediatrics journal, september-2016 (derleme)
7) DOCK8 Levels in Patients with Hyperimmunoglobulin E Sendrome:
Detection by Flow Cytometry
Suzan Çınar, Metin Yusuf Gelmez, Serdar Nepesov, Yıldız Camcıoğlu, Günnur Deniz
Turkish Journal of Immunology 2015;3(2):71-75
8) Development of Anaphylactic Shock After First Exposure to Ceftriaxone
Fatih Aygün, Fatma Deniz Aygün, Serdar Nepesov, Halit Çam, Yıldız Camcıoğlu
Çocuk Dergisi 14(3):128-130, 2014  Case report
9) Leukocyte Adhesion Deficiency III: Report of Two Siblings
Aygun D, Nepesov S, Gershoni R, Camcıoglu Y.
Pediatr Neonatol. 2017 Feb;58(1):99-100.
10)A novel pathogenic frameshift variant of CD3E gene in two T-B+ NK+ SCID patients from Turkey.
Firtina S, Ng YY, Ng OH, Nepesov S, Yesilbas O, Kilercik M, Burtecene N, Cinar S, Camcioglu Y, Ozbek U, Sayitoglu M.
Immunogenetics. 2017 Jun 9. doi: 10.1007/s00251-017-1005-7.
11)The protective role of Helicobacter pylori neutrophil activating protein in childhood asthma
A.Karakullukcu,H.B.Tokman, S.Nepesov,M.Demirci, S.Sarıbaş,S.Vehid,R.Calışkan,
Z.Taner, H.Cokuğraş,T.Ziver,S.Demiryas,B.Kocazeybek
Allergol Immunopathol (Madr) 2017;45:521-7-DOI:10.1016/J.ALLER.2017.01.008
12)Yumurta Alerjisi :Çocuklardaki Özellikleri Nelerdir?
Serdar Nepesov ,Haluk Çokuğraş
Çocuklarda Besin Alerjileri: kitabı, Editör:Prof.Dr.Nermin Güler ,Selen Yayıncılık s.67-75, 2017
13)Hışıltılı Çocuğa Yaklaşım
Serdar Nepesov ,Haluk Çokuğraş
Klinik Tıp Pediatri dergisi: mart-nisan 2017 cilt:9 sayı:2 (derleme)
14)Sık Hastalanan Çocuğa Yaklaşım
Yıldız Camcioğlu , Serdar Nepesov
Çocuk Enfeksiyonlarına Güncel Yaklaşımlar :kitabı,Editör:Prof.Dr.Ayper Somer,Selen Yayıncılık s.92-100, 2017
15) Probiyotikler ve Enfeksiyon: Mİkrobiyota Regülasyonu.
İşeri Nepesov M, Dinleyici M, Nepesov S, Kılıç Ö, Dinleyici EÇ.
Mikrobiyota İmmünolojisi. Ankara: Türkiye Klinikleri; 2018. p.108-12.
16) Clinical and immunophenotypic characteristics of patients with chromosome 22q11.2 deletion syndrome: a single institution's experience.
Nepesov S, Aygün FD, Küçüksezer U, Taşdemir E, Çokuğraş H, CamcıoğluY.
Turk Pediatri Ars. 2019 Mar 1;54(1):28-34.
17) Clinical and immunological features of 44 common variable immunodeficiency patients: The experience of a single center in Turkey.
Nepesov S, Aygun FD, Firtina S, Cokugras H, Camcioglu Y.Allergol Immunopathol (Madr). 2020 Apr 13:S0301-0546(20)30032
18) Genetic Characteristics, Infectious, and Noninfectious Manifestations of 32 Patients with Chronic Granulomatous Disease.
Aygun D, Koker MY, Nepesov S, Koker N, van Leeuwen K, de Boer M, Kıykım A, Ozsoy S, Cokugras H, Kuijpers T, Roos D, Camcıoglu Y.Int Arch Allergy Immunol. 2020 Jun 8;181(7):540-550.
19) Mutational landscape of severe combined immunodeficiency patients from Turkey.
Firtina S, Yin Ng Y, Hatirnaz Ng O, Kiykim A, Aydiner E, Nepesov S, Camcioglu Y, Sayar EH, Reisli I, Torun SH, Cogurlu T, Uygun D, Simsek IE, Kaya A, Cipe F, Cagdas D, Yucel E, Cekic S, Uygun V, Baris S, Ozen A, Ozbek U, Sayitoglu M.. Int J Immunogenet. 2020 May 22.
20) Decreased frequency of allergy in juvenile idiopathic arthritis: Results of a case-control study
Pinar Ozge Avar-Aydin , Serdar Nepesov , Kenan Barut , Sezgin Sahin , Amra Adrovic , Haluk Cezmi Cokugras , Ozgur Kasapcopur ..Mod Rheumatol 2020 Sep 7;1-7.
21) Kök Hücre Transplantasyonu ve Enfeksiyonlar
Serdar Nepesov, S.Sema Anak, Murat Elli, Yöntem Yaman,Ebru Sarıbeyoğlu.
Hematolojide Destek Tedaviler kitabı, Editör:Güner Hayri Özcan
Türk Hematoloji Derneği yayını, s.247-302, 2020
22) Mikobakteriyel hastalıklara Mendelyen duyarlılık
Serdar Nepesov, Yıldız Camcıoğlu
Klinik Tıp Pediatri dergisi, Cilt: 12 Sayı: 2 Mart - Nisan 2020 (derleme)
23) Primer İmmün Yetersizlikler  veya  İmmün Sistemin Doğuştan Kusurları’nda 
Aşılama Önerileri.
Yıldız Camcıoğlu, Serdar Nepesov
Klinik Tıp Pediatri dergisi, 2020 (derleme) yayın aşamasında.
24) Clinical Efficacy of Ruxolitinib Monotherapy and Haploidentical Hematopoeitic Stem Cell Transplantation in a Child with Philadelphia Chromosome-like Relapsed/Refractory acute lymphoblastic leukemia
Nihan Bayram , Yöntem Yaman , Kürşat Özdilli , Leyla Telhan , Serdar Nepesov , Hülya Bilgen , Murat Elli , Sude Sema Behar , Sema Anak
Pediatr Transplant2021 Jun;25(4):e14024. doi: 10.1111/petr.14024.
25) Primary antibody deficiencies in Turkey: molecular and clinical aspects
Sinem Firtina  Yuk Yin Ng , Ozden H Ng , Ayca Kiykim , Esra Yucel Ozek , Manolya Kara , Elif Aydiner , Serdar Nepesov , Yildiz Camcioglu , Esra H Sayar , Ezgi Yalcin Gungoren , Ismail Reisli , Selda H Torun , Sule Haskologlu , Tuba Cogurlu , Aysenur Kaya , Sukru Cekic , Safa Baris , Ugur Ozbek , Ahmet Ozen , Muge Sayitoglu
Immunol Res 2022 Feb;70(1):44-55.doi: 10.1007/s12026-021-09242-z. Epub 2021 Oct 7.
26) Evolution and long-term outcomes of combined immunodeficiency due to CARMIL2 deficiency.
Kolukisa B, Baser D, Akcam B, Danielson J, Bilgic Eltan S, Haliloglu Y, Sefer AP, Babayeva R, Akgun G, Charbonnier LM, Schmitz-Abe K, Kendir Demirkol Y, Zhang Y, Gonzaga-Jauregui C, Jimenez Heredia R, Kasap N, Kiykim A, Ozek Yucel E, Gok V, Unal E, Pac Kisaarslan A, Nepesov S, Baysoy G, Onal Z, Yesil G, Celkan TT, Cokugras H, Camcioglu Y, Eken A, Boztug K, Lo B, Karakoc-Aydiner E, Su HC, Ozen A, Chatila TA, Baris S.
Allergy. 2022 Mar;77(3):1004-1019. doi: 10.1111/all.15010. Epub 2021 Jul 30.
27) Clinical, Genetic, and Outcome Characteristics of Pediatric Patients with Primary Hemophagocytic Lymphohistiocytosis.
Nepesov S, Yaman Y, Elli M, Bayram N, Özdilli K, Kıykım A, Çakır D, Kılıç B, Aydın K, Ayaz A, Telhan L, Anak S.
Turk Arch Pediatr. 2022 Jul;57(4):398-405. doi: 10.5152/TurkArchPediatr.2022.21314.
28) Diagnosis of primary immunodeficiency diseases in pediatric patients hospitalized for recurrent, severe, or unusual infections.
Nepesov S, Firtina S, Aygun FD, Burtenece N, Cokugras H, Camcioglu Y.
Allergol Immunopathol (Madr). 2022 Jul 1;50(4):50-56. doi: 10.15586/aei.v50i4.605. eCollection 2022.
29)SARS-CoV-2-related MIS-C: A key to the viral and genetic causes of Kawasaki disease?
Sancho-Shimizu V, Brodin P, Cobat A, Biggs CM, Toubiana J, Lucas CL, Henrickson SE, Belot A; MIS-C@CHGE, Tangye SG, Milner JD, Levin M, Abel L, Bogunovic D, Casanova JL, Zhang SY.
J Exp Med. 2021 Jun 7;218(6):e20210446. doi: 10.1084/jem.20210446.
30) Chronic Neutropenia in Childhood: Laboratory and Clinical Features.
Nepesov S, Yaman Y, Elli M, Bayram N, Ozdilli K, Ayaz A, Anak S.
Indian J Pediatr. 2022 Sep;89(9):894-898. doi: 10.1007/s12098-022-04104-4. Epub 2022 Mar 10.
31) Eltrombopag for treatment of thrombocytopenia after allogeneic hematopoietic cell transplantation in children: Single-centre experience.
Yaman Y, Elli M, Şahin Ş, Özdilli K, Bilgen H, Bayram N, Nepesov S, Anak S.
Pediatr Transplant. 2021 Aug;25(5):e13962. doi: 10.1111/petr.13962. Epub 2021 Jan 16.
31) Inflammatory Bowel Disease and Guillain Barre Syndrome in FCHO1 Deficiency.
Aydemir S, Islek A, Nepesov S, Yaman Y, Baysoy G, Beser OF, Cokugras FC, Baris S, Karakoc-Aydiner E, Cokugras H, Hubrack SZ, Kendir Demirkol Y, Lo B, Kiykim A, Ozen A.
J Clin Immunol. 2021 Aug;41(6):1406-1410. doi: 10.1007/s10875-021-01042-2. Epub 2021 May 5.
32) HLA - matched related donor hematopoietic stem cell transplantation in a patient with polynucleotide kinase 3-phosphatase mutation developed acute myeloid leukemia.
Bayram N, Yaman Y, Elli M, Ozdilli K, Nepesov S, Dogan MS, Ayaz A, Anak S.
Pediatr Transplant. 2022 Jun;26(4):e14255. doi: 10.1111/petr.14255. Epub 2022 Feb 21.
32) Hematopoietic Stem Cell Transplantation in Patients with Severe Combined Immunodeficiency:
A Single-Center Experience
Serdar Nepesov , Yöntem Yaman , Murat Elli , Nihan Bayram , Kurşat Ozdilli , Ayça Kıykım , Sema Anak Experimed 2022; 12(1): 24-8
33)Impaired IL-23-dependent induction of IFN-γ underlies mycobacterial disease in patients with inherited TYK2 deficiency.
Ogishi M, Arias AA, Yang R, Han JE, Zhang P, Rinchai D, Halpern J, Mulwa J, Keating N, Chrabieh M, Lainé C, Seeleuthner Y, Ramírez-Alejo N, Nekooie-Marnany N, Guennoun A, Muller-Fleckenstein I, Fleckenstein B, Kilic SS, Minegishi Y, Ehl S, Kaiser-Labusch P, Kendir-Demirkol Y, Rozenberg F, Errami A, Zhang SY, Zhang Q, Bohlen J, Philippot Q, Puel A, Jouanguy E, Pourmoghaddas Z, Bakhtiar S, Willasch AM, Horneff G, Llanora G, Shek LP, Chai LYA, Tay SH, Rahimi HH, Mahdaviani SA, Nepesov S, Bousfiha AA, Erdeniz EH, Karbuz A, Marr N, Navarrete C, Adeli M, Hammarstrom L, Abolhassani H, Parvaneh N, Al Muhsen S, Alosaimi MF, Alsohime F, Nourizadeh M, Moin M, Arnaout R, Alshareef S, El-Baghdadi J, Genel F, Sherkat R, Kiykim A, Yücel E, Keles S, Bustamante J, Abel L, Casanova JL, Boisson-Dupuis S.J Exp Med. 2022 Oct 3;219(10):e20220094. doi: 10.1084/jem.20220094. Epub 2022 Sep 12
34)Diagnosis of primary immunodeficiency diseases in pediatric patients hospitalized for recurrent, severe, or unusual infections.

Nepesov S, Firtina S, Aygun FD, Burtenece N, Cokugras H, Camcioglu Y.Allergol Immunopathol (Madr). 2022 Jul 1;50(4):50-56. doi: 10.15586/aei.v50i4.605. eCollection 2022
35)GENETIC AND CLINICAL PROFILING OF MENDELIAN SUSCEPTIBILITY TO MYCOBACTERIAL DISEASE PATIENTS; SINGLECENTER EXPERIENCE
Serdar NEPESOV,Sinem FIRTINA,Deniz AYGÜN,Begüm IŞIKGİL,Yıldız CAMCIOĞLU ,Ayça KIYKIM,Esra ÖZEK,Yasemin KENDİR DEMİRKOL,Akif Ayaz ARAŞTIRMA MAKALESİ / RESEARCH ARTICLE Journal of Advanced Research in Health Sciences / Sağlık Bilimlerinde İleri Araştırmalar Dergisi 2022 DOI: 10.26650/JARHS2022-1119899
Uluslararası Posterler
1)Identıfıcation of genetic varıation by targedted next generation sequencıng ın Turkısh SCID patıents

Sinem Fırtına,Serdar Nepesov,Yıldız Camcıoğlu,Y.Y.Ng 

ESİD Barcelona 21-24 september 2016
2)Clinical Aspects of 11 Turkısh Patıents with Digeorge syndrome
Serdar Nepesov,Deniz Aygun, Haluk Çokuğraş, Yıldız Camcıoğlu
ESİD Barcelona 21-24 september 2016
3)Chronic Granulomatous Disease: Experience from  a single PID Center
Serdar NEPESOV¹,  Fatma Deniz FAYGÜN, Yavuz KÖKER², Berkay SARAYMEN², Haluk ÇOKUĞRA޹, Yıldız CAMCIOĞLU¹
ECİ meeting Vienna -2015
4)A case with TACI mutation
Serdar Nepesov1, Deniz Aygun1, Emre Taşdemir2, Haluk Çokuğraş1, Ozden Hatırnaz3, Sinem Sisko3, Sinem Fırtına3, Uğur Özbek3, Yıldız Camcıoğlu1
3rd International Molecular Immunology & Immunogenetics Congress (MIMIC-III)
21-24 april 2016
5)Agammaglobulinemia  Developing  After Rituximab  Treatment
Serdar Nepesov1, Deniz Aygün1, Emre Özer2, Haluk Çokuğraş1, Yıldız Camcıoğlu1
3rd International Molecular Immunology & Immunogenetics Congress (MIMIC-III)
21-24 april 2016
6)Clınıcal And Immunologıcal Features Of 31 Pedıatrıc Parıents Wıth Common Varıable Immundefıcıency
Serdar Nepesov, Haluk Çokuğraş, Necla Akcakaya, Yıldız Camcıoğlu
ESİD Prague, Czech Republic  29 October -1 November 2014

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